This image displays the red, slightly scaly, and elevated lesions on the cheeks and nose in systemic lupus erythematosus. This image displays redness and deep red-purple lesions on the cheeks and nose in a "butterfly" distribution typical of systemic lupus erythematosus. This image displays bleeding from small capillaries under the nail in a person with systemic lupus. This image displays deep red and purple skin lesions due to inflammation of blood vessels with systemic lupus erythematosus. This image displays how inflammation in systemic lupus can be intense, causing very red skin lesions. This image displays the cheeks and nose of a patient affected by systemic lupus that has been aggravated by exposure to the sun. The rash of systemic lupus often involves the hands, as displayed in this image. This image displays a case of lupus on the backs of the hands, worsened by sun exposure. The dull red patches of systemic lupus are prominent in sun-exposed areas. When these patches are seen on the cheeks, one can imagine why the term “butterfly rash” is used.
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Systemic Lupus Erythematosus  Information for adults

Picture of Systemic Lupus Erythematosus: This image displays the red, slightly scaly, and elevated lesions on the cheeks and nose in systemic lupus erythematosus. Divider line
This image displays the red, slightly scaly, and elevated lesions on the cheeks and nose in systemic lupus erythematosus.
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Who's At Risk
Systemic lupus erythematosus can occur in people of all ages, all races, and both sexes. However, it is far more common in women, especially those between 15–45 years old. In America, it is also more commonly seen in people with darker skin than in light-skinned people.

Although it is not directly inherited, lupus and other autoimmune diseases may run in families. Inheriting certain genes may make some people more susceptible to developing lupus.

In addition, certain environmental factors may trigger lupus in those who have a family (genetic) tendency toward the disease, including:
  • Ultraviolet light, especially sunlight
  • Certain medications, especially hydralazine and procainamide
  • Infections
  • Antibiotics, especially penicillins or sulfa-containing medicines
  • Stress
  • Hormonal changes, especially related to pregnancy and menstrual cycles
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Last Modified: 22 Dec 2008
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