Pemphigus vulgaris frequently affects the inner lining of the mouth (oral mucosa); in this image, there is loss of the top layer of skin (epidermis) of the lip. Close-up of the skin blisters and skin erosions of pemphigus vulgaris. Pemphigus vulgaris can have scattered skin sores called erosions. The erosions can develop crusts (scabs). Crusting and loss of the skin of the lip frequently occurs with pemphigus vulgaris. Painful ulcers of the inner lining of the mouth (mucosa of the oral cavity) can occur in pemphigus vulgaris. Close-up of oral ulcers from pemphigus vulgaris.
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Pemphigus Vulgaris  Information for adults

Picture of Pemphigus Vulgaris: Pemphigus vulgaris frequently affects the inner lining of the mouth (oral mucosa); in this image, there is loss of the top layer of skin (epidermis) of the lip. Divider line
Pemphigus vulgaris frequently affects the inner lining of the mouth (oral mucosa); in this image, there is loss of the top layer of skin (epidermis) of the lip.
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Self-Care Guidelines
Self-care measures for pemphigus vulgaris are as follows:
  • Keep wounds clean – Be very gentle and do not use harsh cleansers.
  • If bandaging is necessary, use bandages that provide moisture and protection, or keep the skin moist with sterile lotions. Silicone bandages, such as those used in burn centers, can be useful. Bandages should allow for airflow but protect against contaminants.
  • Avoid touching ointment and bandages.
  • Do not use bandages that are dry or stick to your skin.
  • Avoid spicy foods (eg, garlic and onions) and nuts, which may help relieve symptoms.
  • Antibiotic ointment or cream can help treat infection – An antibiotic that includes a local painkiller can bring some relief of pain associated with pemphigus vulgaris.
  • Oral rinses and ointments can be used to reduce pain in the mouth.
Be sure to ask your doctor for advice on dealing with the side effects of corticosteroids and other immune suppressants.
When to Seek Medical Care
It is very important to get an accurate confirming diagnosis as soon as possible, so see your doctor if you display any of the signs or symptoms discussed here or suspect you might have pemphigus vulgaris. Early expert diagnosis is important, as pemphigus vulgaris – as with other autoimmune diseases – becomes more resistant to treatment if it is not promptly and appropriately controlled.
Last Modified: 17 Feb 2009