Pemphigus vulgaris frequently affects the inner lining of the mouth (oral mucosa); in this image, there is loss of the top layer of skin (epidermis) of the lip. Close-up of the skin blisters and skin erosions of pemphigus vulgaris. Pemphigus vulgaris can have scattered skin sores called erosions. The erosions can develop crusts (scabs). Crusting and loss of the skin of the lip frequently occurs with pemphigus vulgaris. Painful ulcers of the inner lining of the mouth (mucosa of the oral cavity) can occur in pemphigus vulgaris. Close-up of oral ulcers from pemphigus vulgaris.
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Pemphigus Vulgaris  Information for adults

Picture of Pemphigus Vulgaris: Pemphigus vulgaris frequently affects the inner lining of the mouth (oral mucosa); in this image, there is loss of the top layer of skin (epidermis) of the lip. Divider line
Pemphigus vulgaris frequently affects the inner lining of the mouth (oral mucosa); in this image, there is loss of the top layer of skin (epidermis) of the lip.
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Who's At Risk
Pemphigus vulgaris affects men and women approximately equally. Although sometimes appearing in younger people, the average onset of symptoms is in those aged 50–60 years. Pemphigus vulgaris can occur in persons of any ethnicity, but the disorder tends to appear more often in persons of Mediterranean ancestry, Ashkenazi Jews, and some subtypes in people from Brazil and Colombia.

Pemphigus vulgaris is categorized as an ultra-orphan disease (meaning it is very rare), affecting approximately 10,000–30,000 people in the United States.
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Last Modified: 17 Feb 2009
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