This image displays widespread raised and flat lesions coming together into larger lesions typical of drug rashes (eruptions).  This image displays a typical drug eruption in an infant. Widespread pink lesions are typical of urticarial drug eruptions.
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Drug Eruption, Unclassified (Pediatric)  A parent's guide for infants and babies

Picture of Drug Eruption, Unclassified (Pediatric): This image displays widespread raised and flat lesions coming together into larger lesions typical of drug rashes (eruptions).  Divider line
This image displays widespread raised and flat lesions coming together into larger lesions typical of drug rashes (eruptions).
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Treatments Your Provider May Prescribe
If your child's physician suspects a drug rash, he or she may want to establish the correct diagnosis by performing a biopsy of the lesion. The procedure involves:
  1. Numbing the skin with an injectable anesthetic.
  2. Sampling a small piece of skin by using a flexible razor blade, a scalpel, or a tiny cookie cutter (called a "punch biopsy"). If a punch biopsy is taken, a stitch (suture) or two may be placed and will need to be removed 6–14 days later.
  3. Having the skin sample examined under the microscope by a specially trained physician (dermatopathologist).
In addition, the doctor may want to do blood tests and look for signs of an allergic reaction.

The best treatment for a drug rash is to stop the medication that is causing it. After your child stops taking a medicine, it may take 5–10 days to see an improvement in the skin and up to 3 weeks for the rash to go away completely.

Note: Do not have your child stop taking a prescription medication until the doctor advises you to do so.

Other treatments that may be helpful include:
  • Oral antihistamine pills or syrups such as diphenhydramine, hydroxyzine, loratadine, cetirizine, fexofenadine, or desloratadine for itching.
  • Topical corticosteroid (cortisone) creams or lotions for red, inflamed skin.
  • Topical antibiotic ointments for open sores.
Last Modified: 22 Dec 2008