Baby Acne (Neonatal Acne)  A parent's guide for infants and babies

In mild cases, prescription therapy is generally unnecessary, and the lesions may resolve with gentle cleansing of the skin. The first-line treatment most physicians prescribe is 2.5% benzoyl peroxide. This is an gel that is applied to the skin; it is a commonly used acne product. It is generally well tolerated but may cause dryness. The next line of therapy, in severe cases, is to add an oral antibiotic. Most infants are able to stop oral antibiotics within 18 months. Rarely, cases of acne could be made worse by a fungus, which would require a topical antifungal applied to the skin for treatment. Your baby's pediatrician may request the help of a pediatric dermatologist for severe cases of acne. Furthermore, in severe cases or those resistant to therapy, an investigation for an underlying hormonal (endocrine) disorder may be warranted.